Peer-reviewed research

The science behind ReJI.

Explore the published research that underpins Reactive Jet Impingement bioprinting, from high-cell-density gel formation to structured co-cultures and application studies.

Diagram of the Reactive Jet Impingement bioprinting process

Research foundations

Trace claims back to the paper.

These publications were produced by researchers involved in developing and applying ReJI technology, primarily through Newcastle University collaborations. They are presented as scientific evidence, not as proof of a finished commercial product or universal performance.

Publication library

Peer-reviewed ReJI research

Open each DOI to review the publisher record, methods and full evidence boundary.

01
2026Process characterisationJournal of the Mechanical Behavior of Biomedical Materials

Effect of bio-ink physical properties on droplet volume in the reactive jet impingement 3D bioprinting system

Ozdemir Steedman et al.

Examines how viscosity and surface tension relate to ReJI droplet volume, including the processing of cell-filled hydrogel systems.

DOI10.1016/j.jmbbm.2026.107471
02
2026Cartilage researchBiomaterials Science

Bioprinting chondrocyte hydrogel cultures onto fibre membranes for cartilage defect repair

Ozdemir Steedman, Ferreira, Melo and Dalgarno

Studies ReJI deposition of chondrocyte-containing hydrogels onto collagen membranes and the control of cell distribution and density.

DOI10.1039/D6BM00467A
03
2024High-cell-density modelsInternational Journal of Molecular Sciences

Bioprinted High-Cell-Density Laminar Scaffolds Stimulate Extracellular Matrix Production in Osteochondral Co-Cultures

Bowes et al.

Demonstrates ReJI-produced laminar co-cultures with defined interfaces and investigates extracellular matrix production.

DOI10.3390/ijms252011131
04
2023Cell deliveryBiomaterials Advances

Cell seeding via bioprinted hydrogels supports cell migration into porous apatite-wollastonite bioceramic scaffolds for bone tissue engineering

Kotlarz, Melo, Ferreira, Gentile and Dalgarno

Compares ReJI hydrogel-based cell seeding with conventional seeding and studies migration into porous bioceramic scaffolds.

DOI10.1016/j.bioadv.2023.213532
05
2019Foundational ReJI researchBiofabrication

Reactive jet impingement bioprinting of high cell density gels for bone microtissue fabrication

Da Conceicao Ribeiro et al.

Introduces reactive jet impingement bioprinting for high-cell-density hydrogel deposition and bone microtissue fabrication.

DOI10.1088/1758-5090/aaf625

Evidence in context

Published research is one part of commercial confidence.

01

Scientific basis

Peer review helps establish the process, methods and observed research outcomes.

02

Application fit

A new model still requires application-specific materials, controls, readouts and success criteria.

03

Commercial proof

Repeatability, usability, support and transfer must be demonstrated for the intended workflow.

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